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Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid (HA). Karl Meyer classified these enzymes in into three distinct groups



How does Hyaluronidase Work? (buy hyaluronidase online uk)

Hyaluronidase works as an enzyme to temporarily break down hyaluronic acid which is found naturally in the body. This makes it easier for injection of fluids to be administered, and effective absorption of the fluids into the skin and tissue.

Hyaluronidases additionally aids the body to  reabsorb blood and fluids from the tissues, in the case of a large bruise.

What's in the box? | buy hyaluronidase online uk

What are the benefits of Hyaluronidas? | buy hyaluronidase online uk

Hyaluronidas are a family of enzymes that catalyse the degradation of hyaluronic acid (HA). Karl Meyer classified these enzymes in 1971 into three distinct groups, a scheme based on the enzyme reaction products. The three main types of hyaluronidases are two classes of eukaryotic endoglycosidase hydrolases and a prokaryotic lyase-type of glycosidase

In humans, there are five functional hyaluronidases: HYAL1HYAL2HYAL3, HYAL4 and HYAL5 (also known as SPAM1 or PH-20); plus a pseudogene, HYAL6 (also known as HYALP1). The genes for HYAL1-3 are clustered in chromosome 3, while HYAL4-6 are clustered in chromosome 7. HYAL1 and HYAL2 are the major hyaluronidases in most tissues. GPI-anchored HYAL2 is responsible for cleaving high-molecular weight HA, which is mostly bound to the CD44 receptor. The resulting HA fragments of variable size are then further hydrolized by HYAL1 after being internalized into endo-lysosomes; this generates HA oligosaccharides.

According to their enzymatic mechanism, hyaluronidases are hyaluronoglucosidases (EC, i.e. they cleave the (1->4)-linkages between N-acetylglucosamine and glucuronate. The term hyaluronidase may also refer to hyaluronoglucuronidases (EC, which cleave (1->3)-linkages. In addition, bacterial hyaluronate lyases (EC4.2.2.1) may also be referred to as hyaluronidases, although this is uncommon.

1 review for Hyaluronidase

  1. Rated 5 out of 5

    Robert M. Roche

    Whilst there is a wide range of good…
    Whilst there is a wide range of good products available, my recent order was after paying out of stock and after 2 months I still did not receive it , it took a lot of emails and I had to change my order to another product as my two preferred items were no longer available and this cost more .saying that the order came quickly once sorted , but not ideal .I will use this company again but if I continue to have these problems i will go elsewhere .

    • Filler Shop Team

      Hi Robert,

      I am sorry to hear that you have had some difficulties with your order. Please get in touch with us and we can look further into this for you as a matter of urgency.

      Kindest regards

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